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prednisolone phosphate gel 0.5% |
Orchapred Overview
The first steroidal eye gel in the market designed to deliver better anti-inflammatory effect.
Orchapred gel achieves more anti-inflammatory efficacy with less frequent applications for moderate to severe inflammations.
Indications
- Post-operative
- Inflammation of the palpebral & bulbar conjunctiva
- Allergic conjunctivitis ( vernal keratoconjunctivitis)
- Corneal injuries from chemicals, radial & thermal burns or penetration of foreign bodies.
- Keratitis ( superficial punctuate, Herpes zoster, stromal & peripheral corneal erosions)
- Episcleritis & Scleritis
- Iritis, Iridocyclitis & Cyclitis
Description
Orchapred gel is composed of prednisolone sodium phosphate 5mg/g
Dosage
The recommended dose is three times daily at minimum approach.
Note: The adjustment of the dose is according to the severity of the case.
How does Orchapred gel work?
Its new advanced vehicle is a mucoadhesive gel (Carbomer 3mg/g + Polyvinyl alcohol 10mg/g).
The Carbomer and tear mucin interact and form non-covalent bonds which trap in the PVA forming the three dimensional hydrogel meshwork.
The hydrogel formula increases the amount of prednisolone penetration into the cornea and aqueous humour.
The gel vehicle will provide
- Increase in the viscosity of the drops.
- Reduction in the drainage of the drops.
- Prolonged precorneal contact time.
- Enhanced drug bioavailability, thus an increase in concentration in the intraocular tissues.
- Reduced frequency of administration.
- A soothing effect upon application.
* For more details, check the Orchapred insert....
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